Research in the Butterworth lab is focused on the regulation of ion channels in epithelial cells of the body. We have particular expertise investigating the epithelial sodium channel (ENaC) and its regulation in the kidney and airway. Defects in salt and water transport across epithelial cells result in numerous diseases including cystic fibrosis and defective blood pressure regulation. Our lab aims to understand these defects by investigating cellular responses to hormonal signals. Our most recent projects have focused on the role of non-coding RNAs in this hormonal regulation.
You will find out more about us and our work on this site (tabs/menus at the top). Students interested in rotation projects should look at the research tab where we list oppertunities.
Department of Cell Biology
200 Lothrop St, Pittsburgh, PA